Based on the provided details for 'Apex, 2021', there is insufficient information to determine the presence or evaluate the portrayal of LGBTQ+ characters and themes within the film.

There is insufficient information available to assess the portrayal of transsexual characters or themes in 'Apex, 2021'. No details regarding their presence or depiction were provided, preventing a determination of net impact. For example, no character arcs or plot points related to transsexual identity were found.

The film features female characters, notably West, who participates in the hunt. However, there are no clear instances depicted where a female character defeats one or more male opponents in direct physical combat, such as hand-to-hand or melee weapon fights. Combat primarily involves firearms.

The provided information does not indicate that 'Apex, 2021' is an adaptation of existing source material or a biopic. Without prior canon or historical figures to establish character genders, it is not possible to determine if any gender swaps occurred.

Apex (2021) is an original film, not an adaptation or historical piece. Its characters were created for this specific movie, meaning there are no pre-existing canonical or historical racial baselines to establish a race swap.