Chennai Express does not feature any identifiable LGBTQ+ characters or themes. The narrative centers on a heterosexual romance and action-comedy, with no elements related to queer identity or relationships, resulting in no portrayal to evaluate.

Chennai Express does not feature any identifiable transsexual characters or themes. The film's narrative is centered on a romantic comedy and action plot, leading to an N/A rating for its portrayal of transsexual identity.

The film features Meenamma, the primary female character, who is involved in action sequences but does not engage in or win direct physical combat against male opponents. Her role is not centered on martial prowess.

Chennai Express is an original film, not an adaptation or a reboot of pre-existing characters. All characters were created for this specific movie, meaning there is no prior canon or historical baseline from which a gender swap could occur.

Chennai Express is an original film with no pre-existing source material, historical figures, or prior adaptations. All characters were created specifically for this movie, thus precluding any race swaps.