The film's central conflict critiques government bureaucracy and corporate interests for impeding access to life-saving treatments, championing individual initiative and self-organized solutions over systemic reform. This emphasis on individual liberty and skepticism of regulation aligns with right-leaning themes.

The movie features traditional casting that aligns with its historical setting and real-life inspirations, without explicit race or gender swaps of established roles. Its narrative focuses on a white, heterosexual male protagonist's journey through the AIDS crisis, critiquing systemic failures and societal prejudice while prominently featuring a transgender character and the struggles of marginalized communities.