Date Movie features Andy, a gay character whose portrayal relies heavily on harmful stereotypes for comedic effect. His identity is primarily a source of superficial humor, reducing him to a caricature rather than a complex individual. This depiction lacks dignity and contributes to a net negative impact on LGBTQ+ representation, aligning with the film's broader use of ridicule.

Date Movie includes a transsexual character named "Tranny," whose portrayal is highly problematic. The character's name is a derogatory slur, and her depiction relies on harmful stereotypes for comedic effect, presenting transsexual identity as a source of mockery and degradation without any affirming or critical counterpoints.

The film features multiple instances where characters, who are parodies of established figures, are portrayed by actors of a different race than their source material counterparts. Examples include Frank Jones (parodying Gus Portokalos), Roz Jones (parodying Maria Portokalos), Mr. Yamamoto (parodying Mr. Miyagi), and Gandalf.