The film "Fantastic Beasts: The Crimes of Grindelwald" does not feature any identifiable transsexual characters or themes. The narrative focuses on magical conflicts, character backstories, and the wizarding world, without engaging with transsexual identity or experiences in any capacity.

The film features several female characters who participate in magical duels and confrontations. However, their victories and engagements are primarily achieved through the use of magic, not through direct physical combat, hand-to-hand fighting, or melee weapon skills against male opponents.

The film features established characters from the Wizarding World, including Albus Dumbledore and Nicolas Flamel, all of whom retain their canonical genders. While some characters' timelines are adjusted, no character established as one gender in prior canon is portrayed as a different gender.

The film introduces new characters like Nagini and Leta Lestrange whose races were not established in prior Harry Potter canon. All pre-existing characters with an established race are portrayed by actors of the same race.