The film depicts a warm and supportive friendship between the titular Frog and Toad, who share a domestic life. While their close bond has been interpreted by some as having queer undertones, the narrative itself does not explicitly identify them as LGBTQ+ characters or feature overt LGBTQ+ themes. The portrayal focuses on their deep friendship.

The film 'Frog and Toad Are Friends' does not include any identifiable transsexual characters or themes. Its narrative centers on the simple, everyday adventures and friendship of two male anthropomorphic amphibians, Frog and Toad, without addressing gender identity.

The movie does not contain any action or adventure elements.

The 1985 animated film adaptation of "Frog and Toad Are Friends" maintains the canonical gender of its main characters, Frog and Toad, as established in Arnold Lobel's original books. No significant characters underwent a gender change from the source material.

The film's main characters, Frog and Toad, are anthropomorphic animals. The concept of human race, as defined for a 'race swap,' does not apply to these characters, and no human characters are present or depicted with a changed race.