Halloween Kills does not feature any identifiable LGBTQ+ characters or themes. The narrative is solely dedicated to the slasher plot, focusing on Michael Myers and the Strode family's struggle, resulting in no depiction of queer identity.

Halloween Kills does not include any identifiable transsexual characters or themes. The narrative focuses on the ongoing conflict between Laurie Strode and Michael Myers, and the town's reaction, without incorporating transgender identities or experiences.

The film features several female characters who encounter Michael Myers, including Allyson Nelson and Lindsey Wallace. While some attempt to fight back, none are depicted as victorious in direct physical combat against Michael or any other male opponent. Characters who engage in combat are either defeated or part of a group effort that ultimately fails.

Halloween Kills features returning legacy characters from the 1978 original, such as Laurie Strode, Tommy Doyle, and Lindsey Wallace. All these characters maintain their established genders from the source material. No character canonically established as one gender is portrayed as a different gender.

All legacy characters in "Halloween Kills" are portrayed by actors of the same race as their original depictions in prior installments. No established characters underwent a race change.