Based on available information, 'Hand of Dante' does not appear to feature explicit LGBTQ+ characters or themes. There is no indication of LGBTQ+ representation in plot summaries or cast details, leading to a determination of N/A for its portrayal.

Based on available information, the film 'In the Hand of Dante' does not appear to feature any transsexual characters or themes. The plot and character descriptions focus on a crime drama involving a manuscript, mob bosses, and historical figures, with no mention of gender identity or transformation. Therefore, there is no identifiable portrayal to evaluate.

The movie does not contain any action or adventure elements.

The provided information indicates that 'Hand of Dante' portrays main roles, including historical figures and fictional characters, in their traditional gender identities. No evidence suggests any character canonically, historically, or widely established as one gender is depicted as a different gender. Therefore, no gender swaps are identified.

The film features a diverse cast, but the provided information explicitly states there is no explicit mention or documentation of race-swapping for any characters from their original historical or literary depictions.