Inland Empire does not depict any identifiable LGBTQ+ characters or themes. The film's narrative primarily focuses on themes of identity, reality, and psychological fragmentation, without engaging with sexual orientation or gender identity.

Inland Empire does not feature any identifiable transsexual characters or themes. The narrative focuses on an actress's descent into a fragmented reality, exploring themes of identity, performance, and the nature of reality without engaging with transsexual experiences.

The movie does not contain any action or adventure elements.

Inland Empire is an original film by David Lynch, not an adaptation, reboot, or biopic. All characters were created for this film, meaning there is no prior canon or historical record to establish a baseline gender for any character to be swapped from.

Inland Empire is an original film with characters created specifically for this production. There is no prior source material, historical record, or previous installment from which characters' races could have been established and subsequently changed.