M*A*S*H features a prominent comedic sequence involving a mock same-sex wedding and cross-dressing, intended to prevent a suicide. This portrayal uses non-normative gender expression and same-sex intimacy as a source of ridicule and absurdity, rather than offering any affirming or respectful depiction of LGBTQ+ themes. The net impact is negative.

The film presents a nuanced view of Christianity, primarily through Father Mulcahy, who is portrayed with a degree of sympathy despite being a comedic figure, and Frank Burns, whose self-righteous hypocrisy is a target of satire. The narrative clearly condemns Frank's bigoted and cruel behavior, framing his misuse of faith as a personal failing rather than a critique of the religion itself. This distinction positions the audience to reject the character's bigotry while acknowledging the potential for genuine faith.