Monster Hunter does not feature any identifiable LGBTQ+ characters or themes. The film's plot is solely centered on military personnel fighting monstrous creatures, with no narrative elements or character developments related to sexual orientation or gender identity.

The film "Monster Hunter" does not feature any identifiable transsexual characters or themes. The narrative focuses exclusively on action, survival, and monster combat, with no elements related to transgender identity or experiences.

The film primarily features Captain Natalie Artemis fighting various monsters, often with firearms or large melee weapons. While she does engage in physical combat with The Hunter, a male character, she is consistently outmatched and defeated by him in their direct confrontations. There are no instances of a female character defeating male opponents in close-quarters physical combat.

The film introduces new, original characters and adapts archetypes from the game series where player characters have customizable genders. No established canonical characters from the Monster Hunter games were portrayed with a different gender in the movie.