Due to the complete absence of plot details, character information, or thematic descriptions, it is not possible to assess the film's portrayal of LGBTQ+ characters and themes.

Currently, there is not enough information available to assess the film's portrayal of transsexual characters or themes. Without any plot details or character descriptions, it is impossible to identify any specific character arcs or story plots that would support a positive, negative, or neutral rating, thus preventing an assessment.

The movie does not contain any action or adventure elements.

There is no information provided about source material, prior adaptations, or historical figures for "Mother Father Sister Brother Frank." Without this context, it is impossible to determine if any character's gender has been swapped from an established baseline.

There is no information provided about source material, prior adaptations, or historical figures for "Mother Father Sister Brother Frank." Without an established baseline for character races, it is not possible to determine if a race swap has occurred.