Natale in Sudafrica features gay characters whose identities are primarily leveraged for comedic effect. One character's hidden homosexuality serves as a plot twist, while another is portrayed through flamboyant stereotypes. The film uses these elements for humor without offering affirming portrayals or critiquing societal pressures.

The film features a character whose gender identity is used as a source of comedic shock and mockery. The revelation of the character's male identity, after being presented as a woman, elicits negative reactions from other characters, framing the identity as a punchline rather than with dignity or respect.