Prometheus does not include any identifiable LGBTQ+ characters or themes. The narrative focuses on scientific discovery, the origins of humanity, and survival, without incorporating queer identities or experiences into its storyline or character arcs.

The film "Prometheus" does not feature any identifiable transsexual characters or themes within its narrative or character arcs. Consequently, there is no portrayal to evaluate regarding positive, negative, or neutral impact on transsexual representation.

The film features Dr. Elizabeth Shaw and Meredith Vickers in action sequences, but neither character engages in or wins direct physical combat against one or more male opponents. Their challenges involve survival against environmental threats or alien creatures, not hand-to-hand victories over men.

Prometheus introduces new characters within the Alien universe rather than adapting or recasting pre-existing, gender-established characters from prior installments or source material. Therefore, no gender swaps occur.

Prometheus introduces an entirely new cast of characters original to this film within the Alien universe. There are no pre-existing characters from prior source material or history whose race could have been changed.