RRR does not explicitly feature any identifiable LGBTQ+ characters or themes. The intense bond between the two male leads, while interpreted by some as having queer subtext, is presented within the narrative as a profound friendship, not an explicitly LGBTQ+ relationship.

RRR does not feature any identifiable transsexual characters or themes. The narrative is centered on historical fiction and action, with no elements related to transgender identity or experiences.

The film does not feature any significant female characters engaging in or winning direct physical combat against male opponents. Female characters primarily serve supportive or narrative roles, without participating in close-quarters fights.

RRR is a fictionalized historical film featuring characters inspired by real-life male revolutionaries, Alluri Sitarama Raju and Komaram Bheem, who are portrayed as male in the film. Other significant characters are original to the movie, thus lacking prior canonical gender for a swap.

The film features fictionalized versions of real Indian historical figures and original characters. All characters are portrayed by actors whose race aligns with their historical or established depiction within the film's narrative and setting. No instances of a character being portrayed by an actor of a different race than their established canon or historical background were identified.