The film "The Plague Dogs" focuses on the harrowing escape and survival of two dogs from an animal research facility. Its narrative centers on themes of animal cruelty, friendship, and the struggle for freedom. There are no identifiable LGBTQ+ characters, themes, or plotlines present in the film.

The film 'The Plague Dogs' does not feature any identifiable transsexual characters or themes. Its narrative centers entirely on animal welfare, survival, and the relationship between two dogs, making the category of transsexual portrayal not applicable.

The film focuses on two male dog protagonists and their struggle for survival. There are no significant female characters, human or animal, who engage in or win close-quarters physical combat against male opponents.

The animated film "The Plague Dogs" faithfully adapts its source novel. All major characters, including Rowf, Snitter, and The Tod, retain their established genders from Richard Adams' book, with no instances of gender alteration.

The film's primary characters are animals (dogs), who do not possess human racial characteristics. Human characters are minor, and their race was not a canonically established element in the source material that could be subject to a race swap.