The film "Universal Soldier: The Return" is an action movie primarily focused on sci-fi military themes. It does not feature any identifiable LGBTQ+ characters or themes, resulting in no portrayal to evaluate within the scope of this framework.

Universal Soldier: The Return does not feature any identifiable transsexual characters or themes. The narrative is entirely focused on action and science fiction elements, with no content related to transgender identity or experiences. Therefore, the film has no impact on the portrayal of transsexual individuals.

The film features female characters, including a female UniSol named Erin, who participates in combat. However, there are no scenes where a female character is depicted as victorious in close-quarters physical combat against one or more male opponents.

This film is a direct sequel to the 1992 movie. The returning protagonist, Luc Deveraux, maintains his established male gender. All other significant characters are new to this installment and do not represent gender-swapped versions of previously established characters from the franchise.

This film is a sequel where the primary returning character, Luc Deveraux, is portrayed by the same actor, Jean-Claude Van Damme. All other significant characters are new to this installment and thus have no prior established race to be swapped from.