7de Laan has featured significant LGBTQ+ storylines, notably Rickus's coming out and relationships. The show generally portrays these characters with dignity, exploring their challenges with empathy and framing prejudice as an external force, leading to a net positive impact.

7de Laan featured a prominent storyline where the character Willem explored their gender identity and transitioned to Willa. This portrayal aimed to depict the transgender experience with dignity and empathy, contributing to visibility and understanding within a mainstream South African context. The narrative focused on the character's journey of self-discovery and authenticity.

The show frequently depicts characters finding solace, moral guidance, and community through Christian faith and practices. While individual characters may exhibit flaws or hypocrisy, the narrative consistently upholds Christian values as a positive force, often resolving conflicts through themes of forgiveness and redemption.