All My Children was a pioneer in LGBTQ+ representation on daytime television, notably through the long-running, complex, and dignified portrayal of lesbian character Bianca Montgomery and the groundbreaking introduction of transgender character Zoe Luper. The show consistently depicted LGBTQ+ lives with empathy and respect, framing challenges as external societal issues rather than inherent flaws, resulting in a net positive impact.

All My Children featured a groundbreaking storyline in the mid-2000s with the character Zarf/Sarah, a transgender woman. The show depicted her journey of self-acceptance, her romantic relationship, and the challenges she faced with a notable degree of empathy and dignity for its time, contributing to a positive portrayal of transsexual identity on mainstream television.

Christianity is a pervasive and foundational element in the show, often depicted through character backstories, moral dilemmas, and community events. While individual characters may struggle with faith or exhibit hypocrisy, the narrative generally upholds Christian values as aspirational, portraying the faith and its institutions with respect and as a source of comfort and moral guidance.

Judaism is depicted through specific characters and storylines, often exploring interfaith dynamics. The show generally portrays Jewish traditions and cultural identity with respect, integrating them into the diverse fabric of the fictional community without negative narrative framing.