Doctor Who consistently features diverse LGBTQ+ characters, including prominent companions and recurring figures. Their identities are depicted with dignity, complexity, and agency, often integrated naturally into the narrative without being a source of mockery or degradation. The show affirms queer lives and relationships, contributing to a strong positive net impact.

Doctor Who features multiple transsexual characters, most notably Rose Noble and Vitruvia. Their identities are consistently portrayed with dignity, respect, and affirmation by the narrative and other characters. These characters are often depicted as brave, intelligent, and integral to the story, contributing positively to the show's diverse representation.

The show features female characters who are depicted as highly skilled in physical combat. Leela frequently uses hand-to-hand and melee weapons to defeat male opponents, including robots and aliens. River Song also demonstrates martial arts proficiency, overcoming multiple male adversaries in close-quarters engagements.

The central character, The Doctor, historically portrayed by male actors, was recast as a female in 2017. Additionally, the recurring villain The Master, traditionally male, was portrayed as female (Missy) starting in 2014. Both instances constitute clear gender swaps.

The show generally portrays individual Christian faith and its adherents with respect, often as sources of comfort or moral guidance. While it critiques dogmatism or institutional corruption, this is typically framed as a broader critique of power abuse rather than an attack on the faith itself. The narrative often aligns with virtues found within Christian teachings.