The Fallout TV series features subtle yet meaningful LGBTQ+ representation, primarily through Dane, a non-binary character depicted positively and respectfully. The show integrates queerness naturally, avoiding tokenism, and explores themes of social reconstruction that align with inclusive values, contributing to an overall affirming portrayal within its post-apocalyptic world.

The show Fallout features Dane, a non-binary character, depicted with respect and integration as a confident member of the Brotherhood of Steel. Their identity is subtly acknowledged through pronoun usage, without being central to the plot or a source of conflict. This portrayal emphasizes inclusion and avoids stereotypes, presenting an affirming depiction of a trans/non-binary individual within the diverse world-building.

The show features Lucy MacLean engaging in close-quarters physical combat against male opponents. In one notable scene, she fights male raiders using melee combat during an attack on Vault 33, contributing to their defeat.

The film portrays Christianity as a surviving and influential cultural force in the post-apocalyptic world, with adapted rituals and symbols continuing to be practiced. Its depiction is nuanced, exploring its continuity and integration into new societal structures without presenting it as inherently oppressive or foolish.