React to That is a web series focused on people reacting to various videos and content. As a reaction-based show, it does not feature original narrative content or develop its own characters and themes. Therefore, there are no identifiable LGBTQ+ characters or themes present within the show's created content, resulting in an N/A rating for its holistic portrayal.

Based on the provided input, 'React to That' does not contain identifiable transsexual characters or themes. Consequently, an evaluation of its portrayal of such elements cannot be performed, leading to an N/A rating for its net impact.

The movie does not contain any action or adventure elements.

This is a reaction-based show without established canonical characters from prior source material or history. Any individuals featured are new to the show, precluding the possibility of a gender swap as defined.

As a reality/reaction show, "React to That" features real individuals reacting to content rather than fictional characters or historical figures. The concept of a "race swap" does not apply to this format, as there are no established characters with a canonical race to be altered.