Taxi included several storylines featuring gay characters, often as relatives or friends of the main cast. These narratives typically explored the initial discomfort or prejudice of the regular characters, ultimately resolving with a message of acceptance and understanding. The show consistently depicted LGBTQ+ individuals with dignity and used these plots to critique homophobic attitudes, promoting empathy.

The TV show "Taxi" features a transsexual character, Joyce, in one episode. While Joyce is portrayed with some dignity, the narrative primarily focuses on the cis protagonist's shock and discomfort upon learning her identity. The episode includes problematic jokes from other characters and frames Joyce's identity as a source of conflict and difficulty, rather than affirming trans lives or relationships.

The show portrays characters with Christian backgrounds, such as Elaine Nardo, with empathy and nuance. Their moral dilemmas and personal values, often implicitly rooted in Christian ethics, are explored respectfully, without depicting the religion itself as oppressive or foolish.

The show portrays Alex Reiger, a central and generally sympathetic character, as Jewish. His Jewish identity is presented as a normal and respected part of his background, without being subjected to satire or negative stereotypes by the narrative.