The animated series 'The Big Guy and Rusty the Boy Robot' does not feature any identifiable LGBTQ+ characters or themes. The narrative centers on a giant robot protecting the world, without incorporating queer representation.

The animated series "The Big Guy and Rusty the Boy Robot" does not feature any identifiable transsexual characters or themes. The narrative focuses on sci-fi action and the adventures of a giant robot and his sidekick, with no content related to transgender identity.

The animated series primarily features giant robots, Big Guy and Rusty, in combat. While female characters like Dr. Erika Slate are present and contribute significantly to the plot, they do not engage in direct physical combat against male opponents. Their roles are typically scientific or supportive, not involving hand-to-hand or melee weapon fights.

The animated series maintains the established genders of its core characters from the original comic book series. No significant characters who were canonically male or female in the source material are portrayed as a different gender in the show.

The animated series "The Big Guy and Rusty the Boy Robot" adapts its characters from the comic book source material without altering their established or implied racial depictions. No characters canonically established as one race were portrayed as a different race.