The High Fructose Adventures of Annoying Orange is an animated comedy series centered on talking fruit characters. The show does not include any discernible LGBTQ+ characters or themes within its narrative, resulting in no depiction to evaluate.

The animated series "The High Fructose Adventures of Annoying Orange" does not feature any identifiable transsexual characters or themes. Its narrative focuses on comedic interactions between anthropomorphic fruits, with no content related to gender identity.

The animated series primarily features comedic scenarios involving anthropomorphic fruits. Female characters, such as Passion Fruit, are present but do not engage in or win direct physical combat against male opponents. The show's narrative does not include scenes of hand-to-hand fighting or melee weapon use.

The animated series adapts characters from the original web series, maintaining their established genders. No character canonically established as one gender is portrayed as a different gender in this adaptation.

The characters in 'The High Fructose Adventures of Annoying Orange' are anthropomorphic fruits. As such, they do not possess a human race, making the concept of a 'race swap' inapplicable to this series.