The Late Late Show with James Corden includes LGBTQ+ individuals as guests and in various segments, treating them with general respect. Their queer identity is typically present but not central to the show's narrative, and the overall portrayal avoids strong positive or negative arcs, resulting in a neutral impact.

The Late Late Show with James Corden has occasionally featured transgender guests and discussions. These instances have generally been handled with respect, integrating trans individuals into the broader guest lineup without making their identity the primary focus or source of humor. The show's overall impact on trans themes is considered neutral, as it neither consistently champions nor denigrates trans identity.

As a mainstream talk show, 'The Late Late Show with James Corden' generally maintains a respectful and affirming tone towards guests' personal beliefs. When Christianity is discussed by guests, the show's narrative framing, through the host's demeanor and guest interactions, consistently treats expressions of faith with dignity and sympathy, aligning with a positive portrayal.