Bisho provides an empathetic and nuanced portrayal of a young man's sexual awakening and exploration of his queer identity. The film depicts a complex same-sex relationship and the protagonist's internal and external struggles with dignity. It frames challenges as external societal pressures, affirming the worth of LGBTQ+ lives and love through its respectful and non-judgmental lens.

The film portrays a fractured family dealing with grief and estrangement, questioning traditional gender roles and parental authority through its exploration of a strained mother-son relationship and the legacy of a deceased father. It depicts complex family realities rather than endorsing traditional norms.

The film critiques the conservative societal norms prevalent in Mexico, which are heavily influenced by Catholicism. These religiously-informed norms are depicted as restrictive and oppressive to the protagonist's journey of self-discovery and identity, particularly regarding sexuality, with the narrative implicitly positioning these pressures as problematic.