Blade Runner 2049 does not feature any explicitly identifiable LGBTQ+ characters or themes within its narrative. The film explores universal themes of identity, humanity, and artificial intelligence, but these are presented without specific reference to queer experiences or relationships. Consequently, the film's net impact on LGBTQ+ portrayal is N/A.

Blade Runner 2049 does not feature any identifiable transsexual characters or themes. The narrative focuses on artificial intelligence, replicant identity, and humanity, without engaging with transgender experiences or issues.

Blade Runner 2049 introduces new characters and features returning characters (Deckard, Rachael, Gaff) who maintain their established genders from previous installments and source material. No character canonically established as one gender is portrayed as a different gender.

Blade Runner 2049 primarily features new characters whose races were not established in prior canon. Legacy characters like Rick Deckard and Gaff are portrayed by their original actors, maintaining their established racial depictions.