Chicago Cab includes a brief, incidental depiction of a gay male passenger who discusses his life and relationship. His identity is presented factually and without judgment, contributing to the film's mosaic of human experiences without being central or carrying strong positive or negative implications.

The film includes a character identified as a 'transvestite' who shares her life with the cab driver. The portrayal is humanizing, allowing the character to express her identity and struggles with dignity. While using outdated terminology, the scene avoids overt mockery or degradation, resulting in a neutral overall impact.

The film portrays Christian characters, particularly a young woman grappling with a moral dilemma, with significant empathy and nuance. It explores their internal struggles and faith as integral parts of their identity without ridiculing or condemning their beliefs, aligning the narrative with the dignity of their personal journeys.