The film 'Ed, Edd n Eddy's Big Picture Show' does not include any discernible LGBTQ+ characters or themes. Its narrative centers on the main trio's quest, without exploring aspects of sexual orientation or gender identity.

Ed, Edd n Eddy's Big Picture Show is an animated comedy film centered on the misadventures of three friends. The story does not feature any identifiable transsexual characters or themes, nor does it address issues of gender identity. Consequently, there is no portrayal to evaluate under the provided rubric.

The film is a continuation of the animated series "Ed, Edd n Eddy." All established characters maintain their original genders from the series, and no new characters introduced exhibit a gender swap from prior canon or source material.

The film is an animated continuation of the original series, maintaining the established visual depictions and racial characteristics of all its characters. No character's race was altered from their prior canonical portrayal.