The film "Escape Room" does not feature any identifiable LGBTQ+ characters or themes. The narrative focuses on a group of strangers navigating deadly escape rooms, with no explicit or implicit LGBTQ+ representation present in the plot or character arcs.

The film 'Escape Room' does not feature any identifiable transsexual characters or themes. The narrative is centered on a survival game and the personal traumas of its participants, none of which are related to transgender identity. Therefore, there is no portrayal to evaluate.

The film features female characters, but none are depicted engaging in or winning close-quarters physical combat against one or more male opponents using skill, strength, martial arts, or melee weapons. Victories are achieved through puzzle-solving or the use of specific devices.

Escape Room (2019) is an original film featuring new characters created specifically for this story. There are no pre-existing source materials, historical figures, or prior installments from which characters' genders could have been established and subsequently changed.

Escape Room (2019) is an original film with characters created specifically for this installment. There is no prior source material, historical figures, or previous adaptations from which character races were established. Therefore, no race swaps occurred.