Godzilla x Kong: The New Empire does not feature identifiable LGBTQ+ characters or themes. The film primarily focuses on monster mythology and human alliances, with no direct address of LGBTQ+ representation in its content or casting choices.

Godzilla x Kong: The New Empire does not feature any direct representation of transsexual characters or the trans community. While some viewers have developed allegorical interpretations, particularly regarding Godzilla's changing colors, these readings are external and not explicitly supported by the film's narrative or dialogue. Therefore, the film has no identifiable transgender themes present.

The film features prominent female characters such as Dr. Ilene Andrews and Jia, who are central to the narrative through their scientific expertise, leadership, and unique bond with Kong. However, these characters do not engage in direct physical combat against any male opponents. The action sequences primarily involve giant monsters.

The film features established characters like Godzilla, Kong, Jia, and Dr. Ilene Andrews, whose genders remain consistent with their prior portrayals. No information suggests any character, human or monster, previously established as one gender has been depicted as another in this installment.

The film primarily features original human characters created for the MonsterVerse. There are no instances of established legacy characters from prior Godzilla or King Kong canon being portrayed by actors of a different race, thus no race swaps are identified.