Good Neighbor Sam is a romantic comedy centered on heterosexual relationships and mistaken identities. The film does not feature any identifiable LGBTQ+ characters or themes, resulting in no portrayal of queer identity within its narrative.

Good Neighbor Sam does not feature identifiable transsexual characters or themes. A cisgender male character cross-dresses as a disguise for comedic purposes, but this is a temporary plot device, not an exploration of gender identity. Consequently, the film offers no portrayal of transsexual identity.

The movie does not contain any action or adventure elements.

The film "Good Neighbor Sam" is an adaptation of Jack Finney's 1963 novel. All major characters in the film retain the same gender as established in the original source material, with no instances of a character canonically one gender being portrayed as another.

The 1964 film "Good Neighbor Sam" is an adaptation of a 1963 novel. There is no evidence that any character's race, as established in the source material, was changed for the film adaptation.