Due to a complete lack of available plot summaries, character details, or thematic information for 'Guadalupe, 2023', it is not possible to determine if the film features LGBTQ+ characters or themes, or to evaluate their potential portrayal.

There is currently insufficient information available regarding the plot or characters of 'Guadalupe, 2023' to determine the presence or nature of transsexual depictions. Therefore, an assessment of its overall portrayal cannot be made at this time, as no specific character arcs or story plots can be identified.

The movie does not contain any action or adventure elements.

The film features a young woman named Guadalupe as its protagonist. There is no indication that this character, or any other significant character, was previously established as a different gender in source material, history, or prior adaptations. The character 'Guadalupe' appears to be an original creation for this film.

The film's title refers to Our Lady of Guadalupe, a figure historically depicted as indigenous/mestiza. The lead actresses are Mexican and align with this racial background. There is no indication that a character with an established race is portrayed as a different race.