Guess Who's Coming to Dinner does not feature any identifiable LGBTQ+ characters or themes. The film's central conflict and narrative arcs are entirely centered on racial prejudice and the societal acceptance of an interracial couple in the 1960s.

The film "Guess Who's Coming to Dinner" focuses on themes of interracial marriage, societal prejudice, and generational differences. There are no identifiable transsexual characters or themes present in the narrative, nor are there any depictions that relate to transgender identity or experiences.

The movie does not contain any action or adventure elements.

Guess Who's Coming to Dinner is an original film from 1967, not an adaptation or reboot. Its characters were created for this specific movie, meaning there is no prior source material or historical record from which their gender could have been established differently. Therefore, no gender swaps occurred.

The film "Guess Who's Coming to Dinner" is an original story, not an adaptation of pre-existing material or a biopic. All characters were created for this specific production, meaning there is no prior canonical or historical race to establish a baseline for a race swap.