Killers of the Flower Moon primarily focuses on the racial, social, and political injustices experienced by the Osage Nation. Based on available information, the film does not include any significant or explicit LGBTQ+ characters or themes within its narrative or historical context, resulting in no portrayal to evaluate.

Killers of the Flower Moon does not feature transsexual characters or themes within its narrative. The film's focus is entirely on the historical events concerning the Osage Nation and their struggles, rather than gender identity or the trans community.

The movie does not contain any action or adventure elements.

The film portrays real historical figures, such as Mollie Burkhart and Ernest Burkhart, in their historically accurate gender roles, with no evidence of gender-swapped characters or altered gender identities from the historical record.

The film is a historical drama centered on the Osage Nation, explicitly aiming for authentic representation of historical figures and communities. The provided information states that it avoids race-swapping and portrays characters consistent with their documented historical racial identities.