Love Again features LGBTQ+ characters in supporting, stereotypical roles, such as a "mouthy gay co-worker" and an "overly-aggressive sibling." These characters serve as peripheral comic relief or supportive figures for the heterosexual leads, without exploring queer identities or themes in depth. The portrayal is conventional and incidental, neither significantly affirming nor actively problematic.

The film is an adaptation of a German novel/film where characters were presumably white European. The lead character, Mira Ray, and supporting characters Suzy Ray and John are portrayed by actors of Indian, mixed Black/white, and Black descent, respectively, constituting race swaps from the source material.