Major Grom: Plague Doctor does not include any discernible LGBTQ+ characters or themes. The narrative focuses entirely on its central plot of crime-fighting and social commentary, with no elements related to queer identity present in the story.

The film "Major Grom: Plague Doctor" does not feature any identifiable transsexual characters or themes. The narrative focuses on a police major combating a vigilante, with no elements related to transgender identity present in the story.

The film features strong female characters like Yulia Pchelkina and Maria, who contribute significantly to the plot through their intelligence and leadership. However, neither character engages in or wins direct close-quarters physical combat against male opponents. The action sequences primarily involve male characters.

The film adapts the "Major Grom" comic series. All major characters, including Igor Grom, Sergei Razumovsky, and Yulia Pchelkina, retain their established genders from the original source material in the movie.

Based on a review of the film's main characters and their comic book counterparts, no instances were found where a character canonically established as one race was portrayed as a different race in the movie adaptation.