The film 'Never Say Never Again' does not feature any identifiable LGBTQ+ characters or themes. The narrative is centered on traditional espionage and heterosexual relationships, with no elements pertaining to queer identity or experiences, resulting in no discernible impact on LGBTQ+ representation.

The film "Never Say Never Again" does not feature any identifiable transsexual characters or themes. Its narrative focuses on a traditional spy thriller plot involving espionage and nuclear threats, without engaging with gender identity issues.

The film features female characters such as Domino Petachi and Fatima Blush. While Fatima Blush is an antagonist involved in action, her methods are primarily ranged weapons and explosives. No female character is depicted winning a close-quarters physical combat encounter against one or more male opponents.

This film is a remake and adaptation of existing James Bond material. All major characters, including James Bond, Domino, Largo, and others, retain their canonically established genders from the source novel and previous film adaptation.