Spider-Man: Homecoming does not feature any identifiable LGBTQ+ characters or themes within its narrative. The film focuses on Peter Parker's coming-of-age story and superheroics, with no explicit or implicit portrayal of queer identities or experiences, resulting in an N/A rating for LGBTQ+ depiction.

Spider-Man: Homecoming does not feature any identifiable transgender characters or themes. The film's narrative centers on Peter Parker's high school life and his early adventures as Spider-Man, including his conflict with the Vulture, without exploring aspects of gender identity or transsexual experiences. Consequently, there is no portrayal to assess.

The film does not feature any female characters engaging in direct physical combat. All significant action sequences involve male characters fighting other male characters, with no instances of a female character defeating male opponents in close-quarters combat.

No established legacy characters from Spider-Man comics or prior adaptations undergo a gender change in this film. All major characters maintain their canonical gender.