Teenage Sex and Death at Camp Miasma presents a queer psychosexual slasher that places LGBTQ+ identity at the center of its narrative. The film follows a queer director whose fixation on a reclusive final girl sparks a blood-soaked journey of desire and self-discovery. It reframes classic horror tropes through themes of sexuality, trans identity, and resistance to transphobia, offering affirming portrayals of queer and transgender lives.

The film features a trans-coded masked killer named Little Death whose identity fuels the slasher narrative, reinforcing the longstanding trope of transgender characters as violent threats in horror cinema.

Teenage Sex and Death at Camp Miasma centers its story on sexual awakening, desire, and queer identity within a horror-comedy framework, without depicting or examining marriage, parenting, gender roles in the home, or other family structures.