The Darkest Minds does not feature any identifiable LGBTQ+ characters or themes. The narrative centers on a heterosexual romance and the struggle of superpowered teenagers in a dystopian society, with no queer representation.

The film "The Darkest Minds" does not feature any identifiable transsexual characters or themes within its plot or character arcs. Consequently, there is no portrayal of transsexual identity to evaluate as positive, negative, or neutral.

The film features several female characters with superpowers who engage in combat. However, their victories against male opponents are consistently achieved through the use of their psychic or elemental abilities, not through skill, strength, or martial arts in close-quarters physical combat.

The film adapts the novel series by Alexandra Bracken. A review of the main and supporting characters reveals no instances where a character canonically established as one gender in the source material is portrayed as a different gender in the movie.

The protagonist, Ruby Daly, was not explicitly described as a specific race in the source novels. Therefore, her portrayal by a Black actress does not constitute a race swap according to the provided definition, which excludes characters whose race was never specified in prior canon.