The Last Black Man in San Francisco primarily explores themes of friendship, gentrification, and the search for home through the experiences of Jimmie Fails and Mont. The narrative does not feature any identifiable LGBTQ+ characters or explicit queer themes.

The film "The Last Black Man in San Francisco" does not feature any identifiable transsexual characters or themes within its narrative. Therefore, an assessment of its portrayal of transsexual identity cannot be made, as there is no depiction to evaluate.

The movie does not contain any action or adventure elements.

The Last Black Man in San Francisco is an original story with characters created for the film. There is no prior source material, historical figures, or previous installments from which character genders could be established and then swapped.

The film is an original story, not an adaptation of existing material or a biopic of historical figures. The characters are new creations for this film, thus there is no prior established race to compare against for a race swap.