The Pickup does not contain any identifiable LGBTQ+ characters or themes. The film's narrative is centered on its heist plot and the relationships between its primary characters, with no notable LGBTQ+ representation or subplots present, resulting in an N/A rating for LGBTQ+ portrayal.

The Pickup (2025) does not feature any transsexual characters or explore themes of gender or sexual transformation. The story is an action-comedy heist, focusing on armored truck drivers and criminals, with no elements pertaining to transgender identities or issues.

Based on the available information, specific details about female characters engaging in and winning close-quarters physical combat against male opponents are not provided. While Zoe is a leader in an action-oriented plot, her direct combat victories are not explicitly described.

The provided information indicates that "The Pickup" features original characters, such as Zoe, with no prior established canon or history. There is no mention of characters being adapted from source material or previous installments where their gender was different. Therefore, no gender swaps are noted.

The provided information explicitly states that no race-swapping is suggested in "The Pickup." The film's casting aligns with actors' racial and ethnic identities, indicating no alteration of established character races.