No plot details or character information were provided for "The Zodiac Murders." Therefore, it is not possible to evaluate the film's portrayal of LGBTQ+ characters or themes, resulting in an N/A rating.

The film "The Zodiac Murders" does not feature any identifiable transsexual characters or themes. The narrative focuses on the investigation of the Zodiac Killer, and there is no indication of transgender representation within its plot or character arcs, leading to a determination of N/A for its portrayal.

The movie does not contain any action or adventure elements.

The film's title suggests a focus on the historical Zodiac Killer, who was consistently perceived as male in source materials. Without specific plot or character details for this 1975 film, there is no evidence to indicate any established character's gender was changed.

The 1975 film "The Zodiac Murders" is a fictionalized account of real-world events. There is no evidence of specific, canonically established characters (from prior source material or historical record) being portrayed by actors of a different race within this film.