Torrente 4: Lethal crisis features a protagonist whose homophobic views and use of slurs are central to its comedic style. LGBTQ+ characters or themes are often presented as caricatures or targets for derogatory humor, reinforcing harmful stereotypes. The film's overall portrayal endorses ridicule rather than offering a nuanced or affirming perspective.

Torrente 4: Lethal crisis features transsexual characters and themes primarily as a source of problematic humor. The film employs harmful stereotypes, slurs, and depicts trans identity as a source of mockery and discomfort for the protagonist, without offering any counterbalancing positive or critical perspective. The net impact is overwhelmingly negative.

The film frequently depicts Catholic cultural elements and figures, often highlighting hypocrisy among adherents or within institutions. Religious settings are used to contrast with the protagonist's immoral actions, contributing to a cynical portrayal rather than affirming the faith's virtues.