The film 'Uncharted' does not include any explicit LGBTQ+ characters or themes. The narrative focuses on action, adventure, and the relationships between its main heterosexual characters, resulting in no discernible LGBTQ+ representation.

The film "Uncharted" does not feature any identifiable transsexual characters or themes. Its narrative is entirely focused on action, adventure, and treasure hunting, with no elements that touch upon transgender identity or experiences. Therefore, the net impact is N/A due to the absence of depiction.

The film adapts characters from the Uncharted video game series. Nathan Drake, Victor Sullivan, and Chloe Frazer all retain their established genders from the source material. New characters introduced in the film do not replace existing characters of a different gender.

The film adapts characters like Nathan Drake and Sully, who are white in the source video games, and they are portrayed by white actors. Chloe Frazer, of Indian descent in the games, is played by an actress of South Asian heritage. No established character's race was changed.