The film features a prominent gay character, Brandon St. Randy, depicted as a confident professional, and a minor gay character, Delaney, without negative framing. While some humor stems from a straight character's discomfort, the overall portrayal of LGBTQ+ identity is neither strongly affirming nor denigrating, resulting in a neutral net impact.

The film includes a transsexual character, 'Tranny,' whose brief appearance is for comedic effect during a casting scene. The portrayal relies on stereotypes and includes the use of a derogatory slur by other characters, presenting the character without dignity or complexity, resulting in a problematic depiction.

The film portrays the character Deacon, a gay porn actor, as a Christian struggling to reconcile his faith with his profession and identity. The narrative treats his internal conflict with empathy and nuance, highlighting the personal journey of faith rather than ridiculing the religion itself or its adherents.