Big Shot features Destiny Winters, a lesbian character whose coming-out story and relationship are depicted with dignity and depth. The narrative sensitively addresses challenges like parental disapproval, ultimately resolving with acceptance and support from her family and team. The show's overall portrayal of LGBTQ+ identity is affirming and positive, emphasizing empathy and inclusion.

Big Shot features Destiny, a transgender student and basketball player, whose storyline centers on her journey of self-acceptance and gaining acceptance from her teammates and coach. The show addresses initial misunderstandings with empathy, ultimately portraying her identity with dignity and affirming the importance of inclusivity within the school and team environment.

The series includes a main character, Destiny, who is Jewish, and depicts her family celebrating Hanukkah as a normal and accepted part of their cultural and religious identity. Her faith is presented respectfully and without negative stereotypes.