Entourage features Lloyd, a prominent gay character, who is frequently subjected to homophobic slurs and jokes by his boss, Ari Gold. While Lloyd is depicted as competent, the show often uses his identity for problematic humor without significant narrative critique. This pervasive, unaddressed ridicule contributes to a net negative portrayal of LGBTQ+ themes.

Entourage includes limited references to transsexual identity, primarily through derogatory language and jokes. These instances contribute to a problematic portrayal, reinforcing negative stereotypes and using trans identity as a source of mockery without offering counterbalancing positive or nuanced representation.

The show portrays Judaism primarily through Ari Gold's cultural identity and family life. While some humor derives from cultural stereotypes, the narrative ultimately presents his Jewish background as a source of strong family values and a grounding influence, contributing to a nuanced character portrayal rather than a negative critique of the faith.